Kiran Krishnan, Microbiologist

Mechanisms of Gut-Brain Axis Dysregulation and Innovative Science on Restoring the Gut-Brain Synergy

We are currently living in the “era of the microbiome”, and there is daily development in understanding of the complex and bi-directional relationship between our guts and our brains-evolving into the popular concept of the Gut-Brain Axis (GBA). The microbiome ecosystem can influence central nervous system physiology through production of anti-inflammatory compounds, maintenance of a strong intestinal barrier, production of neurotransmitters, regulation of stress response, and vagal nerve stimulation. While intricate, this system is delicate. Low gut diversity means less production of signaling molecules and neurotransmitters. The microbial ecosystem can help modulate stress response, but chronic stress can dampen microbial diversity. Thus, there is elaborate two-way cross talk between the gut and the brain and dysfunction in this messaging has strong potential for vicious cycles of ill health- including mental health-in today’s modern world. Fortunately, there are emerging therapeutic tools to “manipulate the microbiome” and improve the connectivity between these two fundamental organs. Learn about these mechanisms and promising new interventions in this talk!

ABOUT KIRAN KRISHNAN

Kiran Krishnan is a Research Microbiologist and has been involved in the dietary supplement and nutrition market for the past 17 years. He comes from a strict research background having spent several years with hands-on R&D in the fields of molecular medicine and microbiology at the University of Iowa. He left University research to take a position as the U.S. Business Development and Product Development lead for Amano Enzyme, USA. Amano is one of the world’s largest suppliers of therapeutic enzymes used in the dietary supplement and pharmaceutical industries in North America. Kiran also established a Clinical Research Organization where he designed and conducted dozens of human clinical trials in human nutrition.

Kiran is also a co-founder and partner in Nu Science Trading, LLC.; a nutritional technology development, research and marketing company in the U.S. Dietary Supplement and Medical Food markets. Most recently, Kiran is acting as the Chief Scientific Officer at Physician’s Exclusive, LLC. and Microbiome Labs. He has developed over 50 private label nutritional products for small to large brands in the global market. He is a frequent lecturer on the Human Microbiome at Medical and Nutrition Conferences. He conducts the popular monthly Microbiome Series Webinars through the Rebel Health Tribe Group practitioner training program, is an expert guest on National Radio and Satellite radio and has been a guest speaker on several Health Summits as a microbiome expert. He is currently involved in 9 novel human clinical trials on probiotics and the human microbiome.

Kiran is also on the Scientific Advisory Board for 5 other companies in the industry. Kiran offers his extensive knowledge and practical application of the latest science on the human microbiome as it relates to health and wellness.

WHERE TO FIND KIRAN KRISHNAN

Q&A

Statement/paragraph of why you are passionate about studying the microbiome and/or what motivated you to begin studying microbiome therapeutics: 
As a microbiologist, it was quite natural for me to understand the awe inspiring capabilities of microbial ecosystems in all aspects of our lives. This power that microbes hold is particularly important in reference to the human system. It became clear to me, over 10 years ago, that the study of the microbiome would hold many of the answers to our most prevalent health questions and in the sane way, the microbiome would present significant healing opportunities. In my view, the way a scientist or clinician can maximize her or his impact is to study and work with the human microbiome. 

Please provide 3 tips you would share with fellow healthcare professionals if asked how to support a consistent healthcare journey for the patients who struggle with staying on the road to success through a tough healing process:
1) build tiny habits. small positive steps add up to a lot of progress
2) understand that healing cannot be expected to happen fast as the damage was done over years. So patience is key and consistency is required.
3) celebrate small victories, this reinforces the commitment and builds a mindset of success. No matter how small, celebrate that victory. Even if it was a single days correct dietary choice, celebrate it.